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Charles J. Bail Histoire politique et morale des revolutions de la France. T. 2


Полный вариант заголовка: «Histoire politique et morale des revolutions de la France : T. 2 : ou chronologie raisonnee des evenements memorables depuis 1787 jusqu'a la fin de 1820, epoque des Conferences de Troppau et de Laybach / par M. Bail».

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Футболка с полной запечаткой (мужская) Printio Binding of isaac


Футболка с полной запечаткой (мужская) — пол: Муж, материал: Синтетика. Изображение персонажей из видеоигры The Binding of Isaac: Afterbirth.

1190 RUR

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Andrea Bellelli Reversible Ligand Binding. Theory and Experiment


Presents the physical background of ligand binding and instructs on how experiments should be designed and analyzed Reversible Ligand Binding: Theory and Experiment discusses the physical background of protein-ligand interactions—providing a comprehensive view of the various biochemical considerations that govern reversible, as well as irreversible, ligand binding. Special consideration is devoted to enzymology, a field usually treated separately from ligand binding, but actually governed by identical thermodynamic relationships. Attention is given to the design of the experiment, which aids in showing clear evidence of biochemical features that may otherwise escape notice. Classical experiments are reviewed in order to further highlight the importance of the design of the experiment. Overall, the book supplies students with the understanding that is necessary for interpreting ligand binding experiments, formulating plausible reaction schemes, and analyzing the data according to the chosen model(s). Topics covered include: theory of ligand binding to monomeric proteins; practical considerations and commonly encountered problems; oligomeric proteins with multiple binding sites; ligand binding kinetics; hemoglobin and its ligands; single-substrate enzymes and their inhibitors; two-substrate enzymes and their inhibitors; and rapid kinetic methods for studying enzyme reactions. Bridges theory of ligand binding and allostery with experiments Applies historical and physical insight to provide a clear understanding of ligand binding Written by a renowned author with long-standing research and teaching expertise in the area of ligand binding and allostery Based on FEBS Advanced Course lectures on the topic Reversible Ligand Binding: Theory and Experiment is an ideal text reference for students and scientists involved in biophysical chemistry, physical biochemistry, biophysics, molecular biology, protein engineering, drug design, pharmacology, physiology, biotechnology, and bioengineering.

8265.76 RUR

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Charles J. Bail Histoire politique et morale des revolutions de la France. T. 1


Полный вариант заголовка: «Histoire politique et morale des revolutions de la France : Tome 1 : ou chronologie raisonnee des evenemens memorables depuis 1787 jusqu'a la fin de 1820, epoque des conferences de Troppau et de Laybach / par M. Bail».

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Футболка с полной запечаткой для девочек Printio Binding of isaac


Футболка с полной запечаткой для девочек. Изображение персонажей из видеоигры The Binding of Isaac: Afterbirth.

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Футболка с полной запечаткой для мальчиков Printio Binding of isaac


Футболка с полной запечаткой для мальчиков. Изображение персонажей из видеоигры The Binding of Isaac: Afterbirth.

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Заглушки для монтажа креплений HOLMENKOL Binding Stopper


Разноцветные заглушки для монтажа креплений.

  • Количество: 500 штук

1470 RUR

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Bridget Collins The Binding

Findlay John W. Ligand-Binding Assays. Development, Validation, and Implementation in the Drug Development Arena


A consolidated and comprehensive reference on ligand-binding assays Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of the pharmaco-kinetics and toxicokinetics of macromolecules, an area of burgeoning interest in the pharmaceutical industry. Yet, outside of the Crystal City Conference proceedings, little guidance has been available for LBA validation, particularly for assays used to support macromolecule drug development. Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena answers that growing need, serving as a reference text discussing critical aspects of the development, validation, and implementation of ligand-binding assays in the drug development field. Ligand-Binding Assays covers essential topics related to ligand-binding assays, from pharmacokinetic studies, the development of LBAs, assay validation, statistical LBA aspects, and regulatory aspects, to software for LBAs and robotics and other emerging methodologies for LBAs. Highlights include: A general discussion of challenges and proven approaches in the development of ligand-binding assays More detailed examination of characteristics of these assays when applied to support of pharmacokinetic and toxicokinetic studies of compounds at different stages in the discovery or development timeline A concise, but detailed, discussion of validation of ligand-binding assays for macromolecules A practical approach to «fit-for-purpose» validation of assays for biomarkers, those molecules receiving increased attention as potentially demonstrating that the target chosen in discovery is being modulated by the candidate therapeutic, both in nonclinical and clinical studies Written by a team of world-recognized authorities in the field, Ligand-Binding Assays provides key information to a broad range of practitioners, both in the pharmaceutical and allied industries and in related contract research organizations and academic laboratories and, perhaps, even in the field of diagnostics and clinical chemistry.

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